Diurnal rhythmicity in biological processes involved in bioavailability of functional food factors
نویسندگان
چکیده
In the past few decades, many types of functional factors have been identified in dietary foods; for example, flavonoids are major groups widely distributed in the plant kingdom. However, the absorption rates of the functional food factors are usually low, and many of these are difficult to be absorbed in the intact forms because of metabolization by biological processes during absorption. To gain adequate beneficial effects, it is therefore mandatory to know whether functional food factors are absorbed in sufficient quantity, and then reach target organs while maintaining beneficial effects. These are the reasons why the bioavailability of functional food factors has been well investigated using rodent models. Recently, many of the biological processes have been reported to follow diurnal rhythms recurring every 24 h. Therefore, absorption and metabolism of functional food factors influenced by the biological processes may vary with time of day. Consequently, the evaluation of the bioavailability of functional food factors using rodent models should take into consideration the timing of consumption. In this review, we provide a perspective overview of the diurnal rhythm of biological processes involved in the bioavailability of functional food factors, particularly flavonoids.
منابع مشابه
Curcumin as a bioactive compound: biological properties and encapsulation methods
Curcumin is a bioactive compound from turmeric which has different biological properties and health benefits such as antioxidant, anti-inflammatory, antimicrobial, and anticancer activities. However, the low solubility, poor bioavailability, and rapid degradation under neutral or alkaline pH conditions or when exposed to light, limit the food applications of curcumin. These problems can be solv...
متن کاملAssessment of Circadian Rhythmicity of Respiratory Determinants Related to Diurnal Activities of Children and Adolescents: A Case Study in the City of Isfahan
Background: Diurnal sequences of activities conducted at several locations visited by individuals have an impact on population exposure to air pollution. However, data on individual's movement with a fine time resolution is rare. Methods: In the current study, 399 children and adolescents (aged 11–18 years) from Isfahan city were asked to recall their 24-hour diary during winter and spring 2014...
متن کاملTranscriptome Phase Distribution Analysis Reveals Diurnal Regulated Biological Processes and Key Pathways in Rice Flag Leaves and Seedling Leaves
Plant diurnal oscillation is a 24-hour period based variation. The correlation between diurnal genes and biological pathways was widely revealed by microarray analysis in different species. Rice (Oryza sativa) is the major food staple for about half of the world's population. The rice flag leaf is essential in providing photosynthates to the grain filling. However, there is still no comprehensi...
متن کاملTranskingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis
All domains of life feature diverse molecular clock machineries that synchronize physiological processes to diurnal environmental fluctuations. However, no mechanisms are known to cross-regulate prokaryotic and eukaryotic circadian rhythms in multikingdom ecosystems. Here, we show that the intestinal microbiota, in both mice and humans, exhibits diurnal oscillations that are influenced by feedi...
متن کاملEvaluation of Iron Bioavailability in Caco-2 cell Culture Model: Modification of the Original Method
Background and Objectives: In the original in vitro method for evaluation of iron bioavailability using caco-2 cell model, ferritin formation by cells is considered as a functional indicator of both absorption and utilization of iron. However, as iron is measured in the tested material and then ferritin concentration is measured in caco-2 cell lysate, it is almost impossible to have a concrete ...
متن کامل